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CD1a 抗体 (PE)

This anti-CD1a antibody is a 小鼠 单克隆 antibody detecting CD1a in FACS. Suitable for 人.
产品编号 ABIN238416
发货至: 中国

Quick Overview for CD1a 抗体 (PE) (ABIN238416)

抗原

See all CD1a 抗体
CD1a

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD1a antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

HI149
  • 特异性

    The antibody HI149 reacts with CD1a (T6), a 49 KDa polypeptide associated with β2-microglobulin expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells and some T cell leukemias and lymphomas. The antibody does not react with peripheral blood T and B lymphocytes, monocytes, granulocytes, platelets and erythrocytes.

    纯化方法

    Size-exclusion chromatography.

    免疫原

    Human thymocytes.

    亚型

    IgG1
  • 应用备注

    Suitable for Flow Cytometry analysis of human blood cells using 20 m l reagent / 100 m l of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD1a

    别名

    CD1a

    背景

    CD1a, together with CD1b and c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification.Synonyms: T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a, T6/Leu-6, hTa1, hTa1 thymocyte antigen

    UniProt

    P06126

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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